In human DNA, approximately 20,000 genes code for hundreds of thousands of distinct proteins required for normal tissue development and function. San Diego, California, United States 51-100 Venture - Series Unknown Private www.biosplice.com 5,337 Highlights Total Funding Amount $778M Contacts 69 Employee Profiles 7 Investors 11 Similar Companies 14 Find More Contacts for Biosplice Therapeutics Unlock this story instantly and join 161,500+ biopharma pros reading Endpoints daily and it's free. At least those big pharma partners have looked at the early-stage preclinical data. Please note this link is one-time use only and is valid for only 24 hours. The company manufactures an anti-osteoporosis drug called Lorecivivint, which was going through phase 3 clinical trials as of summer 2021. The German tech investor Kizoo Ventures is committing 300m of its own cash to biotech start-ups working on rejuvenation and healthy lifespan expansion. Published: Mar 26, 2021 That level of fanfare was nowhere to be found on Thursday, when the company added another $120 million to its coffers and quietly changed its name to Biosplice Therapeutics. Based in San Diego, CA, Biosplice is developing small-molecule therapeutics based on pioneering science of alternative pre-mRNA splicing. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for . SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA. Funding Rounds Number of Funding Rounds 5 EDG-5506 is currently being assessed in a Phase I study. Biosplice Therapeutics (Excluding its subsidiaries) has filed 96 patent applications at USPTO so far (Excluding Design and PCT applications). All rights reserved. Biosplice Therapeutics; Organogenesis Holdings; Techfields Pharma; Centrexion Therapeutics; Regeneron; Xalud Therapeutics; Bone Therapeutics; Key Highlights. Biosplice Therapeutics has raised a total of $778M in funding over 5 rounds. S AN DIEGO Biosplice, once the world's most valuable biotech startup, is laying off nearly a quarter of its workforce and has stopped internal development of one of its late-stage medicines, a. Biosplice Therapeutics, Inc. (formerly Samumed, LLC) is a private biopharmaceutical company based in San Diego, California.It was founded in 2008 by Osman Kibar.. Samumed's products in development target novel components of the Wnt signaling pathway. Edgewises lead drug candidate is EDG-5506, an orally administered small molecule designed to address the root cause of dystrophinopathies, in development for the treatment of Becker muscular dystrophy (BMD) and Duchenne muscular dystrophy (DMD). Unlock this story instantly and join 161,500+ biopharma pros reading Endpoints daily and it's free. Stemming from foundational discoveries in Wnt pathway modulation, Biosplice has elucidated novel biology linking CLK/DYRK kinases to the therapeutic regulation of alternative splicing. So they plan to test it in patients with mismatch repair mutations, so the tumors are already making mutations. We'll e-mail you a link to set a new password. Biosplice Therapeutics is a privately held company and is not publicly traded on NYSE or NASDAQ in the U.S. To buy pre-IPO shares of a private company, you need to be an accredited investor. Investing in private companies may be considered highly speculative and involves a high degree of risk, including the risk of substantial loss of investment. Pretzel Therapeutics Launches with $72M to Advance Mitochondrial . Unlock this article along with other benefits by subscribing to one of our paid plans. Youre reading a free article with opinions that may differ from The Motley Fools Premium Investing Services. Biosplice Therapeutics is a clinical-stage biotechnology company focused on developing first-in-class, small-molecule therapeutics based on the pioneering science of alternative pre-mRNA splicing. Alternative splicing is a process of creation of multiple mRNAs out of a single pre-mRNA. Biosplice Therapeutics's latest funding round was a Series B for $120M on April 15, 2021. Under no circumstance shall we have any liability to you for any claims, loss, damage or expenses of any kind arising, out of or in connection with your use of the Website or your reliance on any information provided on the Website. If the company doesn't have early-stage data, maybe isn't in late-stage, so you can, as an investor, look at the early-stage data. Copyright 2023 Forge Global, Inc. All rights reserved. About BiospliceBiosplice is developing first-in-class, small-molecule therapeutics based on pioneering science of alternative pre-mRNA splicing. Investing in private companies may be considered highly speculative and involves high risks including the risk of losing some, or all, of your investment amount. Funds from the IPO and the Series B will support development of the companys oncology pipeline. Keith Speights owns shares of Bristol Myers Squibb. Learn more at https://www.biosplice.com, Corporate Contact:Erich HorsleyBiosplice Therapeutics, Inc.erich.horsley@biosplice.com858-365-0200, GLOBAL MARKETS-US stocks muted, Treasuries dip as inflation worries linger, Stock market news today: Stocks waver after key manufacturing data, Salesforce set to report earnings Thursday, Goldman Sachs tries to reset firm culture after three 'unusual' years, Shipping companies reach $97M California oil spill agreement. The information provided on Xipometer.com (the "Website") is intended for qualified institutional investors (investment professionals) only. Other disorders the company will target with its GeneTac platform will include myotonic dystrophy type-1, and other indications that have yet to be publicly announced. Last years list profiled 15 leaders and included a swath of the industry, such as repeat biotech founder Carolyn Bertozzi, minted as a Nobel laureate just months later. Integrating digital therapeutics early in the asset development process will allow for gathering of clinical data to drive a clearer value proposition that maximizes the potential of both products Mammoth Biosciences, Biosplice Therapeutics, Deel, Alto Pharmacy, Biosplice Therapeutics, Biosplice Therapeutics, Chooch AI, Emergex Vaccines. Biosplice Therapeutics uses 8 technology products and services including HTML5 , Google Analytics , and Vimeo, according to G2 Stack. Biosplice contact info: Phone number: (858) 926-2900 Website: www.biosplice.com What does Biosplice do? Other assets in development include a lead optimization-stage ERK5 targeting the KRAS signaling pathway dubbed IK-175; an AHR antagonist known as IK-175; a kynurenine-degrading enzyme known as IK-412; and IK-007, an EP4 receptor antagonist. With their platform's origins in small molecule-based Wnt pathway modulation, they develop therapeutics to address a range of degenerative diseases, regenerative medicine, and oncology. one-time use only and expires after 24 hours. Stemming from foundational discoveries in Wnt pathway. Digital therapeutics support increased access to safe and effective therapies, providing an untapped opportunity for biopharmaceutical companies to maximize the value of medicinal assets and drive differentiation Biosplice Therapeutics is in the medical research and development for tissue-level regeneration. On our trusted digital marketplace for private companies. CIOs and business technology executives at this event will also discuss how men Shanghai Everest Medicines in-licensed a BTK inhibitor for renal diseases from Sinovent and SinoMab Bio for $561 mln. Boston-based Ikena said it expects to raise $125 million from the IPO. Design said it expects to raise approximately $240 million from the IPO, a little bit higher than the $228 million the company previously anticipated. Biosplice, a former anti-aging unicorn, slashes staff in latest episode of its long fall from grace Kyle Blankenship Anti-aging startup Biosplice has had quite the downhill stumble after. You better start looking for another job, the scientist said. Bioscience & Technology Business CenterThe University of KansasLawrence, Kansas. In this case, Keytruda was being used as a treatment both before and after surgery. Biosplice Therapeutics currently has Phase 3 clinical trials in knee osteoarthritis and androgenic alopecia, and a Phase 1 trial for advanced solid tumors. Biosplice Therapeutics is an American pharmaceutical company engaged in the development of alternative splicing technologies. San Francisco Bay Area, Silicon Valley), Operating Status of Organization e.g. Merck revealed on Wednesday that a Phase III trial investigating Keytruda for patients with stage II, IIIA or IIIB non-small cell lung cancer hit its event-free survival primary endpoint. This week began with four biopharma companies announcing intentions to become publicly traded companies and its ending with three companies making their debut on the Nasdaq. The malignant cells permeated his bones, kidney, lungs and liver, and in December, his oncologist told him there was no point in continuing chemotherapy treatment. 308 followers 310 connections. AT-GAA consists of biologic cipaglucosidase alfaand miglustat, a stabilizer of the biologic. Samumed rebrands to Biosplice, raises $120 million, founder leaves. About Mammoth Biosciences Stock. Jan 3, 2023 06:30am. Take like 20mg of zinc that will help reduce the massive prolactin spike that causes the itch. I did find one that has filed an S-1, Candel Therapeutics, that's in phase 3 development; it's using nonreplicating virus to attack tumors. Biosplice Therapeutics was founded in 2021. All trademarks, logos and company names are the property of their respective owners. Now, the biotech is laying off a large swath of its staff as it undergoes a pipeline overhaul. Mammoth Biosciences is a developer of a CRISPR platform for diagnostic, genome editing, and protein discovery applications. Persons. After Novartis acquired AveXis, executives from the leading gene therapy biotech shuffled off to form new startups looking to repeat their Zolgensma story for other diseases. Viking accuses Chinese biotech of 'ruse' to raid trade secrets and make off with NASH cache. Your use of the Website and your reliance on any information on the Website is solely at your own risk. In January, Ikena announced IK-930, a TEAD inhibitor targeting the Hippo signaling pathway, has entered IND-enabling studies. Seed, Series A, Private Equity), Alternate or previous names for the organization, Tags are labels assigned to organizations, which identify their belonging to a group with that shared label, Whether an Organization is for profit or non-profit, General contact email for the organization. Biosplice is developing first-in-class, small-molecule therapeutics based on pioneering science of alternative pre-mRNA splicing. Investment opportunities posted on this website are "private placements" of securities that are not publicly traded, are subject to holding period requirements, and are intended for investors who do not need a liquid investment. Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services. Investors must be able to afford the loss of their entire investment. Just weeks after activist investor Alex Denner called for Amarins chairman to step down, the Irish biotechs shareholders have voted in Denners favor. SaaS, Android, Cloud Computing, Medical Device), Where the organization is headquartered (e.g. Find More Contacts for Biosplice Therapeutics, Edit Lists Featuring This Company Section, After reaching a high with $12B valuation, Biosplice lays off staff and axes baldness program, Live Long(er) And Prosper: A Look At Top VC Investments In Radical Life Extension, Dave Johnson Joins Biosplice Therapeutics Board of Directors, Greater San Diego Area Companies With More Than 50 Employees, Life Science Companies With Fewer Than 100 Employees, United States Companies With Less Than $50M in Revenue (Top 10K). SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA. Samumed made quite the entrance back in 2016, when it launched with some anti-aging programs and a whopping $12 billion valuation. Funds from that round, as well as the IPO, will be used to advance the companys muscular dystrophy program, as well as other indications. This profile is based on publicly available information and is intended to be informative in nature. Anti-aging startup Biosplice has had quite the downhill stumble after debuting to much fanfare back in 2016 under a different moniker. In conjunction with the financing, Joy Ghosh, PhD, of Eventide Asset Management and Gur Roshwalb, MD, of aMoon will be joining the companys Board of Directors. Biosplice Therapeutics does not currently have an official ticker symbol because this company is still private. When he told a group of senior scientists about his ideas for drug delivery at a Chinese restaurant in 1979, one of them blew cigar smoke in his face. | After reaching a $12 billion valuation in 2018 . The data in the tables and charts is based on data from public sources and although we make every effort to compile the data, it may not coincide with the actual data of the issuer. Jan 2017 - Mar 20225 years 3 months. 1 References: (1) Larghi et al., Acta Biomed 2020 (2) Endstrasser et al., ESSKA 2020 . Biosplice Therapeutics, previously known as Samumed, was founded by Turkish American billionaire Osman Kibar and has raised close to $800M from five funding rounds. The biotech boom in the early days of the pandemic helped fuel the rise of Taysha Gene Therapies and Jaguar Gene Therapy, but the winter freeze that followed has also caused a hunkering down for the biotechs, chaired by ex-AveXis CEO Sean Nolan. Merck revealed on Wednesday that a Phase III trial investigating Keytruda for patients with stage II, IIIA or IIIB non-small cell lung cancer hit its event-free survival primary endpoint. Valuations are submitted by companies, mined from state filings or news, provided by VentureSource, or based on a comparables valuation model. La Jolla, California, United States 101-250 Post-IPO Equity Public www.fatetherapeutics.com 3,290 Highlights Stock Symbol NASDAQ:FATE Acquisitions 1 Total Funding Amount $1.2B Contacts 80 Employee Profiles 21 It might be worth that much, but on a risk-adjusted basis, I just don't know. Biosplice Therapeutics Inc - Company Profile and News - Bloomberg Markets Subscribe Live Now Bloomberg TV+ Bloomberg Surveillance: Early Edition Bloomberg Surveillance: Early Edition with Anna. SAN DIEGO, Sept. 29, 2022 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on CLK/DYRK kinase modulation. For decades, MIT professor Robert Langer believed scientists could deliver large molecules such as RNA through tiny particles to treat a range of diseases. 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Holdings ; Techfields pharma ; Centrexion Therapeutics ; Key Highlights drug called Lorecivivint, which was going Phase... Property of their entire investment a Series B will support development of alternative pre-mRNA splicing 2023 Forge Global Inc.! Multiple mRNAs out of a single pre-mRNA ( 2 ) Endstrasser et al., 2020! And healthy lifespan expansion Android, Cloud Computing, Medical Device ) Where. Qualified institutional investors ( investment professionals ) only entire investment pharma partners looked! Unlock this article along with other benefits by subscribing to one of our paid plans the Website your! Least those big pharma partners have looked at the early-stage preclinical data,... After debuting to much fanfare back in 2016, when it launched some. Shareholders have voted in Denners favor by subscribing to one of our paid.!
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