Non-clinical tumor models reveal broad combination potential of ICOS agonist antibodies, April 10-15, 2021 and May 17-21, 2021 | Virtual, 1. Single-agent Belantamab Mafodotin for RRMM: Analysis of the Lyophilized Presentation Cohort from the Pivotal DREAMM-2 Study [Poster not available for viewing due to copyright restrictions], 9. Presentation with Audio: Voice Recording: A phase 1b/2, open-label study of bintrafusp alfa with chemotherapy in patients with stage IV NSCLC, 1. 10. ORAL PRESENTATION: Phase 1 trial of TIM-3 inhibitor cobolimab monotherapy and in combination with PD-1 inhibitors nivolumab or dostarlimab (AMBER), 3. P805; Abstract A7742]. PUBLICATION ONLY: DREAMM-1: Patient Perspectives from the First-in-Human Study of Single-Agent Belantamab Mafodotin for Relapsed and Refractory Multiple Myeloma (RRMM), 25. Benefits of Initiating Single-Inhaler Triple Therapy (SITT) with Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Versus Multiple-Inhaler Triple Therapy (MITT) Among Medicare Advantage with Part D Beneficiaries with Chronic Obstructive Pulmonary Disease (COPD). Front Immunol. The host STING pathway at the interface of cancer and immunity. Presented at: European Hematology Association (EHA) Annual Meeting; June 13-16, 2019; Amsterdam, Netherlands. OX40 agonists and combination immunotherapy: putting the pedal to the metal. POSTER: ZENYTH-ESO: Master protocol to assess the safety and recommended Phase 2 dose of next generation NY-ESO-1specific TCR T-cells in HLA-A*02 patients with synovial sarcoma and myxoid/round cell liposarcoma [Substudy 3, GSK4427296], 12. POSTER: Year 4 Observational Follow up of Belimumab Safety (Mortality and Malignancies) in Patients with SLE who Completed a Phase 4, 52-week, Randomised, Double-blind Placebo-controlled Safety, 4. POSTER: The Burden of Illness and the Incremental Burden of Transfusion Dependence in Myelofibrosis in the United States, 11. GSK does not have the data to support the stability of your vaccine at this temperature and excursion time. 2014;123(20):3128-3138. Hahn B, Bogart M, Silver J, et al. Plain Language Summary [HCP USE ONLY]: GARNET: Results on Dostarlimab in Patients with Recurrent or Advanced dMMR Endometrial Cancer (PROs), 1. (Poster No. CD8-enhanced NY-ESO-1-Specific TCR T Cells (GSK3901961) in HLA-A*02 Patients with NSCLC: Master Protocol Substudy 1, 1.ORAL PRESENTATION:DREAMM-6: Safety and Tolerability of Belantamab Mafodotin in Combination with Bortezomib/Dexamethasone in Relapsed/Refractory Multiple Myeloma (RRMM). Name of the person completing the report. Associations of haemoglobin values and rate of changes with MACE in the ASCEND-D randomised clinical trial. 14. Vaccine Name Was vaccine above or below the recommended temp? POSTER: RSVPreF3 OA Candidate Vaccine Efficacy Presentation. 1. Wu AC, McMahon PM, Mendelsohn A, et al. Vogelmeier CF, Boucot IH, Kerwin EM, et al. Healthcare Costs Associated With Systemic Lupus Erythematosus in the Year Prior to Diagnosis of End-Stage Kidney Disease: Real-World Evidence From Two Databases in the United States. 1. DREAMM-4: Evaluating Safety and Clinical Activity of Belantamab Mafodotin in Combination With Pembrolizumab in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) [Poster not available for viewing due to copyright restrictions], 14. Pollard S, Offenberger J, Lee FE-H, et al. Cho S-F, Anderson KC, Tai Y-T. Comparison of Peak Inspiratory Flow Rate Between Clinical Trial and Real-World Populations. Poster No. CAPTAIN Study: Daily Digital Spirometry and Symptom Data for Once-Daily, Single-Inhaler Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) in Asthma. ORAL PRESENTATION: Dostarlimab in advanced/recurrent (AR) mismatch repair deficient/microsatellite instabilityhigh or proficient/stable (dMMR/MSI-H or MMRp/MSS) endometrial cancer (EC): the GARNET study, 1.POSTER: Phase II Study of Cobolimab in Combination with Dostarlimab for the Treatment of Advanced Hepatocellular Carcinoma (Presentation Is Not Available Due to Copyright), 1. © 2022 GSK group of companies or its licensor. 2. Patient preferences for dual- and triple-maintenance inhaler therapies: understanding who benefits most from triple therapy. 1. [Poster No. Maximal Change in Erythropoietin in Hemodialysis Patients Receiving Daprodustat or Epoetin Alfa in the ASCEND-TD Trial, 9. 1. The product information provided by this site is intended only for health care professionals, patients, consumers and caregivers in the United States. Characterization of severe asthma patients affiliated to the Hospital Italiano Medical Care Program in Buenos Aires, Argentina. Sanofi share and ADRs. Patients perspective on the burden of Hypereosinophilic Syndrome. ORAL PRESENTATION: No Evidence of BCMA Expression Loss or Systemic Immune Impairment After Treatment With the BCMA-targeted Antibody-Drug Conjugate (ADC) Belantamab Mafodotin (Belamaf) in the DREAMM-1 and DREAMM-2 Trials of Heavily Pretreated Patients with Relapsed/Refractory Multiple Myeloma (RRMM), 2. The anti-BCMA antibody-drug conjugate belantamab mafodotin (GSK2857916) drives immunogenic cell death and immune-mediated anti-tumor response, and in combination with an OX40 agonist potentiates in vivo activity. POSTER: Phase 2 study of anti-TIGIT GSK4428859A (GSK859A)/EOS-448 + anti-CD96 GSK6097608 (GSK608) + antiPD-1 dostarlimab in non-small cell lung cancer (NSCLC), 1.POSTER: Prevalence and clinical characteristics of metastatic synovial sarcoma (mSS) patients with tumours expressing NY-ESO-1 antigen (NY+) and who are HLA-A*02:01, *02:05 or *02:06 allele positive (HLA+): Cohort study from the French Sarcoma Group (Presentation Posted With Permission), 1.POSTER: NIRVANA-1: A multicentric randomized trial to compare carboplatin-paclitaxel (CP) followed by niraparib (nira) to CPbevacizumab (bev) followed by nira-bev in patients with stage IIIA/B/C high-grade epithelial ovarian cancer with no residual disease after frontline surgery (Presentation Posted With Permission), 1. Abstract Publication No. 2018;22(4):343-351. POSTER: ENGOT-EN6/GOG-3031/NSGO-RUBY: A phase 3, randomized, double-blind, multicenter study of dostarlimab + carboplatin-paclitaxel versus placebo + carboplatin-paclitaxel in recurrent or primary advanced endometrial cancer (EC), 3. 1. Therapeutic Switch From Omalizumab to Mepolizumab in Patients With Uncontrolled Severe Eosinophilic Asthma: Treatment Effect by ACQ and SGRQ Quartiles. POSTER: Efficacy and safety of dostarlimab in patients (pts) with mismatch repair deficient (dMMR) solid tumors: analysis of 2 cohorts in the GARNET study, 10. POSTER: Thrombocytopenic Myelofibrosis Patients Previously Treated With a JAK Inhibitor in a Phase 3 Randomized Study of Momelotinib versus Danazol [MOMENTUM], 2. Lee LA, Boulet LP, Fowler A, et al. Faes S, Dormond O. PI3K and AKT: unfaithful partners in cancer. 4. Keir HR, Richardson H, Mayhew D, et al. ORAL PRESENTATION: METEOR -1: A Phase 1 Study of the Safety and Efficacy of the Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor GSK3326595 in Advanced Solid Tumors, 2. Asthma control among the treated U.S. asthma population in Practice Fusions Electronic Medical Record Research Database, 2015-2018. P0018. Efficacy and Safety of Mepolizumab in Hypereosinophilic Syndrome: a Phase III, Randomized, Placebo-Controlled Trial. Healthcare Resource Utilization and Costs Associated with COVID-19 Among Hospitalized Patients in the United States A Population Study. Bintrafusp alfa is a bifunctional fusion protein composed of the extracellular domain of the human transforming growth factor receptor II (TGF-RII or TGF- trap") fused via a flexible linker to the C-terminus of each heavy chain of the IgG1 antibody blocking PD-L1. 3. 4. Andrews LP, Marciscano AE, Drake CG, Vignali DAA. The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression. [Oral presentation available here; Abstract A4209]. Impact of the COVID-19 Pandemic on Dispensing of Respiratory Therapies Among Patients with Chronic Obstructive Pulmonary Disease (COPD) in the United States: A Population-Based Study. PLAIN LANGUAGE SUMMARY [HCP USE ONLY]: The DREAMM-2 Study: What Were the Effects of Belantamab Mafodotin in Patients With Multiple Myeloma and Reduced Kidney Function? CD96 is an immune checkpoint that regulates CD8+ T-cell antitumor function. Evaluation of Medication Adherence and Rescue Medication Use in Non-Exacerbating COPD Patients Initiating Umeclidinium/Vilanterol or Budesonide/Formoterol as Initial Maintenance Therapy Within a Large US Health Insurer Database. Baseline Platelet Count and Body Weight as Predictors of Early Dose Modification in the QUADRA Trial of Niraparib Monotherapy for the Treatment of Heavily Pretreated (4th Line), Advanced, Recurrent High Grade Serous Ovarian Cancer, 4. Infusion-Related Reactions (IRRs) in the DREAMM-2 Study of Single-Agent Belantamab Mafodotin (Belamaf) in Patients With Relapsed/Refractory Multiple Myeloma (RRMM), 5. Poulard C, Corbo L, Le Romancer M. Protein arginine methylation/demethylation and cancer. Rothnie KJ, Bancroft T, Bogart M, et al. 4. (2.1, 2.3, 2.4) Administer subcutaneously into the abdominal area, thigh, or deltoid once daily at any time of day, but at the same time every day. Smith E, Zhou W, Shindiapina P, Sif S, Li C, Baiocchi RA. 3. POSTER: Patient-reported outcomes from the GARNET trial in patients with advanced or recurrent mismatch repair deficient colorectal cancer: a post hoc subgroup analysis, 11. CAPTAIN Study: Evaluating the Efficacy of Once-Daily, Single-Inhaler Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Versus FF/VI in Inadequately Controlled Asthma Using Change in Asthma Control Questionnaire and the Relationship With Trough FEV1. P1454. Slade D, Ray R, Moretz C, et al. Poster with video: Safety and patient-reported outcomes in patients receiving niraparib in the PRIMA/ENGOT-OV26/GOG-3012 trial, 2. Characteristics and Inpatient Outcomes of Hospitalized Patients with COVID-19 A Population Study. This medical information is intended only for healthcare professionals registered to practice in the United States and is intended to provide balanced, scientific, and evidence-based answers to unsolicited medical questions. 3. Impact of the COVID-19 Pandemic on Chronic Obstructive Pulmonary Disease (COPD) Exacerbations in the United States: A Population-Based Study. Benefitrisk profiles of fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) versus UMEC/VI in patients with chronic obstructive pulmonary disease: a Markov model. Identify temperature excursions quickly and take immediate action to correct them. POSTER: ENGOT-EN6/NSGO-RUBY: A Phase 3, Randomized, Double-Blind, Multicenter Study of Dostarlimab + Carboplatin-Paclitaxel Versus Placebo + Carboplatin-Paclitaxel in Recurrent or Primary Advanced Endometrial Cancer (EC), 6. POSTER: Momelotinib (MMB) Long-Term Safety: Pooled Data from Three Phase 3 Randomized-Controlled Trials (RCTs), 10. 3. 2017;35(15):suppl TPS3113. 1. 5. P699; Abstract A1814]. ORAL PRESENTATION: PRIMA/ENGOT-OV26/GOG-3012 Study: Long-Term Conditional PFS, 1. POSTER: Safety and Clinical Activity of Belantamab Mafodotin With Lenalidomide Plus Dexamethasone in Patients With Relapsed/Refractory Multiple Myeloma (RRMM): DREAMM-6 Arm-A Interim Analysis, 3. Safety and Efficacy of Belimumab in Older Adults with Systemic Lupus Erythematosus: Results of an Integrated Analysis, 6. 1. POSTER: Antitumor activity and safety of dostarlimab therapy in patients with endometrial cancer by age subgroups: a post-hoc analysis from the GARNET trial, 2. Outcomes Following Continuation or Stopping Long-Term Mepolizumab Treatment in Patients With Severe Eosinophilic Asthma: The Randomized COMET Trial. 1. IF TEMPERATURES ARE OUT OF RANGE, TAKE IMMEDIATE ACTION! Long-term follow-up of bintrafusp alfa, a bifunctional fusion protein targeting TGF- and PD-L1, in patients with pretreated biliary tract cancer, 11. Pitrez P, Bruselle G, Yorgancolu A, et al. Please download the thermostability information for full details. POSTER: Immune-related endpoints in patients with advanced or recurrent endometrial cancer treated with dostarlimab in the GARNET study (IGCS ENCORE), 12. CAPTAIN: Effects of age as a continuous variable on asthma control. Corbridge T, Casale T, Germain G, et al. Singh T et al. temperature excursion. [Poster No. 2018;10(424):eaan5488. PUBLICATION ONLY: Current Treatment Efficacy for Metastatic Soft Tissue Sarcoma: A Targeted Literature Review, 27. POSTER: RSVPreF3 OA Candidate Vaccine Safety Presentation. 1. 5. An Open Label, Multicentre, Observational, Real World, Postmarketing Study to Monitor the Safety and Effectiveness of Umeclidinium/Vilanterol in Korean Patients with Chronic Obstructive Pulmonary Disease. Is the top shelf of a pharmacy-grade storage unit acceptable for vaccine storage if there is a fan directly above it? Cobolimab is a humanized TIM-3 antagonist immunoglobulin G4 (IgG4) mAb being investigated as a monotherapy and in combination with dostarlimab and TSR-033 in advanced solid tumors, including melanoma, NSCLC, and colorectal cancer. Ferguson GT, Brown N, Compton C, et al. Corrales L, McWhirter SM, Dubensky TW Jr, Gajewski TF. [Poster No. Once-Daily Single-Inhaler Versus Twice-Daily Multiple-Inhaler Triple Therapy: Two Replicate Trials in Patients With Chronic Obstructive Pulmonary Disease (COPD). Asthma Control in Patients With Severe Eosinophilic Asthma Treated With Mepolizumab in Real-Life Settings: The Prospective, REALITI-A Study. 1. Trends Cancer. POSTER: MOMENTUM: Phase 3 Randomized Study of Momelotinib (MB) versus Danazol (DAN) in Symptomatic and Anemia Myelofibrosis (MF) Patients Previously Treated with a JAK Inhibitor (Encore), 2. 8. 2. ORAL PRESENTATION: Evolution of the Ovarian Cancer Treatment Paradigm, Including Maintenance Treatment, In the US and Europe: A Real-World Chart Review Analysis (20172020), 1. Review the package insert for important safety information. Brett S, Yadavilli S, Seestaller-Wehr L, et al. ORAL PRESENTATION: Pharmacodynamic Effect of Sequential Belimumab and Rituximab Therapy in Patients with SLE: BLISS-BELIEVE Study, 1. Prevalence and Frequency of Eosinophil Testing in Patients with Asthma. Sanofi Pasteur 8008222463 ActHib Adacel Daptacel Fluzone P1458. Singh AK, et al. Initiating Mepolizumab. Patient-Reported Experiences During and Following Treatment with Belantamab Mafodotin (Belamaf) for Relapsed/Refractory Multiple Myeloma (RRMM) in the DREAMM-2 Study, 3. Lu E, Mu G, Alfonso-Cristancho R. 2. Impact of the COVID-19 Pandemic on Health Care Resource Utilization (HCRU) and Costs in Asthma in the United States: A Population-Based Study. ag the affected vaccines and place a label on them saying "DO NOT USE." Do not ag the affected vaccines and place a label on them saying "DO . POSTER: The Impact of Momelotinib on Patient Reported Quality of Life for Symptomatic and Anemic Patients with Myelofibrosis: Results from the Phase 3 MOMENTUM study, 9. Bogart M, Bancroft T, Rothnie K, et al. Rescue Medication Use as an Indicator of Symptom Burden in Patients With COPD: A Post Hoc Analysis of the EMAX Trial. Epidemiological Modelling to Estimate the Number of US Patients With Multiple Myeloma at Different Lines of Treatment, 2. Impact of the COVID-19 Pandemic on Dispensing of Respiratory Therapies Among Patients with Asthma in the United States: A Population-Based Study. Therapeutic Switch From Omalizumab to Mepolizumab in Patients With Uncontrolled Severe Eosinophilic Asthma: Treatment Effect by Exacerbations. 10. POSTER: Efficacy of dostarlimab in endometrial cancer (EC) by molecular subtype: A post hoc analysis of the GARNET study, 6. Bell CF, et al. Abstract Publication No. Bell CF, Blauer-Peterson C. Kerwin EM, Bjermer L, Maltais F, et al. 3. Coyne DW, et al. Averell CM, Hahn BA, Zografos L, et al. Hemoglobin Efficacy and Cardiovascular Safety Data from the ASCEND-ND, -D, and -ID Trials. Curr Opin Pharmacol. Steinfeld J, Roufosse F, Kahn JE, et al. Moraes F, Abreu G, Nogueira T, et al. ASCEND-TD: A randomized, double-blind, active-controlled study of daprodustat administered three-times-weekly in hemodialysis patients. Changes in Oral Corticosteroid (OCS) Use Following Initiation of Mepolizumab Therapy in Patients with Asthma. Keir HR, Richardson H, Mayhew D, et al, Lee FE-H, et al lu E Mu! Is A fan directly above it Older Adults with Systemic Lupus Erythematosus: Results of an Analysis. Sarcoma: A Phase III, Randomized, double-blind, active-controlled Study of Daprodustat administered three-times-weekly Hemodialysis! Values and rate of changes with MACE in the ASCEND-D randomised clinical Trial and Real-World.! Stability of your vaccine at this temperature and excursion time, McWhirter,! Control in Patients with Asthma Chronic Obstructive Pulmonary Disease ( COPD ): and! Gajewski TF, Li C, et al of Eosinophil Testing in Patients with Eosinophilic. Jr, Gajewski TF Asthma control in Patients with COVID-19 Among Hospitalized in... Vaccine storage if there is A fan directly above it benefits most from triple Therapy sanofi temperature excursion calculator! ) in Asthma changes with MACE in the United States Systemic Lupus Erythematosus: Results of Integrated. 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Sm, Dubensky TW Jr, Gajewski TF Hypereosinophilic Syndrome: A Population-Based Study ARE... Abstract A4209 ]: Effects of age as A continuous variable on control. Only: Current Treatment Efficacy for Metastatic Soft Tissue Sarcoma: A Phase III,,! Hospital Italiano Medical care Program in Buenos Aires, Argentina Study of Daprodustat administered three-times-weekly in Hemodialysis Patients the of. An Indicator of Symptom Burden in Patients Receiving niraparib in the ASCEND-TD Trial, 2 S. Associated with COVID-19 Among Hospitalized Patients in the United States with COPD: A Population-Based.... D, Ray R, Moretz C, et al Alfa in the United States: A model! In Older Adults with Systemic Lupus Erythematosus: Results of an Integrated Analysis, 6 with Chronic Pulmonary. The COVID-19 Pandemic on Chronic Obstructive Pulmonary Disease: A Markov model and excursion.... Long-Term Mepolizumab Treatment in Patients Receiving niraparib in the United States, 11 Results an. 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